Marshall Herff Applewhite, a music professor and seminary dropout raised as the son of a Presbyterian minister, met nurse Bonnie Lu Nettles in 1972, reportedly while he was hospitalised. Applewhite had recently lost a university teaching position over a relationship with a male student and was, by his own and others' accounts, in genuine spiritual crisis. Nettles, going through a divorce, already practised astrology and described ongoing communication with a discarnate monk she said guided her. The two formed an intense, entirely platonic partnership and by 1973 had concluded they were the "Two Witnesses" described in Revelation 11 β sent to prepare humanity for a literal, technological end times.
Over the following years they cycled through names β Bo and Peep, Him and Her, Winnie and Pooh β before settling on Do (Applewhite) and Ti (Nettles), and through group names including Human Individual Metamorphosis and Total Overcomers Anonymous. Their theology synthesised Christian eschatology, science fiction, and 1970s UFO culture into a single claim: that the God and angels of scripture were, in fact, technologically advanced extraterrestrials, and that "the Kingdom of Heaven" was a literal physical destination reachable by spacecraft.